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Selective cellular probes for mammalian thioredoxin reductase TrxR1: rational design of RX1, a modular 1,2-thiaselenane redox probe

Reporter response quantification Reporter response quantification was conducted similar as in Wink et al

Its deficiency can lead to scurvy due to impaired collagen formation affecting bones, blood vessels and skin

These include a history of pancreatitis, severe gastrointestinal conditions such as gastroparesis, gallbladder disease, and reduced kidney function, where dehydration from vomiting or diarrhea is the main concern

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