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Liver-specific benefits of cotadutide have also been reported in T2D patients showing significantly reduced liver fat content by MRI-PDFF (magnetic resonance imaging-proton density fat fraction) as well as significant reductions in circulating collagen fragment, Pro-C3, as a biomarker for liver fibrosis activity and in the FIB4 index, a risk-factor score for fibrosis 11,12,56,57,58,59

Because these reports are voluntary, it is not possible to estimate the frequency of these effects

The Liver: Reversing MASLD/MASH The most revolutionary aspect of Retatrutide is its impact on Metabolically Dysfunctional-Associated Steatotic Liver Disease (MASLD)

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