Rotate through the injection sites
GLP-1 inhibits intestinal contractions through mechanisms that may involve the central nervous system via vagal pathways or direct action on central receptors [24], as well as the enteric nervous system by modulating neurotransmission through presynaptic receptors affecting nitric oxide release [25,26]
Rotating your injection sites between the abdomen, thighs, and upper arms can also prevent lipodystrophy, a condition where fatty tissue builds up and forms hard lumps that may interfere with how your medication is absorbed
In the first week, the main goal is to help your body tolerate the medication
Below, we break down whats currently known
See FDA boxed warning on thyroid C-cell tumors observed in rodent studies, included in the prescribing information for GLP-1 receptor agonists