Common contraindications include personal or family history of medullary thyroid cancer, multiple endocrine neoplasia type 2, or severe gastroparesis
However, substantial heterogeneity among studies was observed, likely attributable to differences in dosage, baseline B12 status, and population characteristics
Some researchers are exploring whether BPC-157 combined with TB-500 might offer complementary neuroprotective and neuroregenerative effects, given TB-500 benefits in tissue repair and inflammation reduction
Finally, there's prolactin
Ipamorelin (10mg) is a selective growth hormone secretagogue acting on the ghrelin receptor, valued in research contexts for its selectivity relative to earlier secretagogues
But the weight gain is not a direct result of the deficiency but rather an indirect result