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Molecules Affecting Glutathione System Ebselen, a nontoxic, seleno-organic drug, is an effective reductant of hydroperoxides

Critically, in non-senescent cells, this interaction is not a survival dependency, so FOXO4-DRI does not trigger apoptosis in healthy cells

doi: 10.1016/j.jobcr.2025.06.006 35 KumarADavuluriGWelchNKimAGangadhariahMAllawyAet al

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When serine and threonine residues within the C truncation were replaced by alanine (Sec24C MUT), VRK2 could not increase phosphorylation of Sec24C MUT (Fig