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Studies confirm 50% drops by midlife, linking to aging symptoms.[1][9] Restoring NAD+ has been shown in animal studies to improve lifespan and healthspan, with human trials indicating benefits in muscle function and cognitive performance

Most people start noticing an improvement in energy levels within 2-3 weeks

The off-days prevent receptor desensitization and allow the pituitary to reset

After the resolution of the deficiency, if patients show clinical or hematologic signs associated with polycythemia vera, it is recommended they undergo further evaluations

AOD 9604/MOTS-c is given as a subcutaneous injection on a provider-determined schedule