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Research shows nausea occurs in 2545% of patients, typically peaking around day 23, while appetite suppression may begin within hours in some individuals

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In a pre- and postnatal development study in pregnant cynomolgus monkeys, subcutaneous doses of 0.015, 0.075 and 0.15 mg/kg twice weekly (1.3-, 6.4- and 14-fold the MRHD) were administered from Gestation Day 16 to 140

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