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Because conversions start conservatively, appetite suppression may feel slightly reduced for a short period while your dose is re-titrated, but this is a deliberate safety measure rather than a setback

Catella-Lawson F et al (2001): Cyclooxygenase inhibitors and the antiplatelet effects of aspirin

Most people do not see scale weight loss in week 1, though appetite suppression begins immediately

It may potentially lead to making it less effective

Its also possible for the combination to bring about side effects that are less common when the drugs are taken separately, given the interaction between the medications mechanisms of action

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