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Its structurally built into the enzyme superoxide dismutase (SOD), and is essential for the functioning of this enzyme, which is our first line of defense against free radical toxins

Characterization of human cytochrome P450 mediated bioactivation of amodiaquine and its major metabolite N-desethylamodiaquine

Aloia TA, Zimmitti G, Conrad C, Gottumukalla V, Kopetz S , Vauthey JN

[DOI] [PubMed] [Google Scholar] 58.Daubeuf S., Leroy P., Paolicchi A., Pompella A., Wellman M., Galteau M.M., Visvikis A

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Limited Clinical Safety Data : The human safety profile remains unclear because the evidence is primarily based on animal and laboratory studies rather than large-scale clinical trials