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Tirzepatide: What It Is and How It Works Tirzepatide is the active ingredient in Mounjaro (approved for type 2 diabetes) and Zepbound (approved for chronic weight management)

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In the ATG5-ATG7-NCOA4 pathway, the process of ferritin-associated autophagy that is mediated by NCOA4 can increase the content of unstable iron in cells, thus promoting ferroptosis 33