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Abstract 14387: dose-related reductions in blood pressure with a RNA interference (RNAi) therapeutic targeting angiotensinogen in hypertensive patients: interim results from a first-in-human phase 1 study of ALN-AGT01

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The lower limit of PRR for the following HLT tumors was invariably greater than 1 in five models: thyroid neoplasms benign and malignant, pancreatic neoplasms malignant (excl islet cell and carcinoid), and islet cell neoplasms and APUDoma NEC (ICN&AN)

Key design improvements ensured high reproducibility of organoid size, morphology, and spatial positioning, establishing a reliable platform for controlled tissue-tissue interactions

171 Radiolabeled with the BoltonHunter reagent at lysine residues, exendin(939) was examined for receptor specificity in vitro and selectivity in vivo

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