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Furthermore, the high heterogeneity of tumors means that different tumor cells exhibit varying degrees of dependence on Gln, resulting in inconsistent sensitivity to these imaging agents

Based on these early studies, induction of apoptosis and autophagy, cell cycle arrest, alterations in the cellular proliferation response and cell signaling, oxidative stress and changes in gene expression have all been proposed as contributing factors

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Additionally, underreporting of mild or transient cases could lead to an underestimation of the true incidence in postvaccination surveillance data

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