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Months 36: This phase showed the most consistent weight reduction in trial data

The two primary methods are subcutaneous (Sub-Q) and intramuscular (IM)

Interleukins (mainly IL-1 and IL-6), interferon- (IFN- ) and tumour necrosis factor (TNF)- , produced by immune cells, endothelial cells, platelets and fibroblasts are associated with atherosclerosis onset and progression

Clinical trials show that headaches occur in approximately 25% of participants, making it one of the more commonly reported side effects during the first few weeks of treatment

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placebo) [61]