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doi: 10.1007/s12012-023-09797-3

[DOI] [PubMed] [Google Scholar] 493.Stueven N.A., Beauvais D.M., Hu R., Kimple R.J., Rapraeger A.C

In Japan, ALS patients received B12 shots of 25,000-50,000mcg (each shot equal to 25-50 pernicious anemia shots all at once), at first daily and then twice a week

However, unlike aspirin (which irreversibly blocks COX), Ace 125 mg appears to indirectly inhibit COX activity and this inhibition is ineffective in the presence of high peroxide concentrations