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Clinical and preclinical studies have demonstrated significant effects on body weight reduction and metabolic regulation, generating considerable scientific interest in its potential role both as a standalone therapy and in combination with GLP-1 receptor agonists for obesity and metabolic disease research

The fat loss it produces may be measurable in clinical settings but is unlikely to produce the kind of visible, health-altering transformation that tirzepatide delivers

(E) Relative gene expression for cells exposed to 10 M SFN for 48 h

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MDA: Malondialdehyde

Berisso GA, van Lint MT, Bacigalupo A, Marmont AM