2013;23(3):2415 Kumar PA, Chitra PS, Reddy GB
Verbal declarative memory dysfunction in schizophrenia: from clinical assessment to genetics and brain mechanisms
Assessment using validated scales can identify patients in need of mental health support
(3) Reduces Inflammatory Markers: It inhibits pro-inflammatory cytokine production, thereby reducing tissue inflammation
Inactivation of DHODH in cancer cells with low GPX4 expression significantly increased intracellular lipid peroxidation, while in cancer cells with high GPX4 expression, DHODH inactivation synergized with inducers to enhance ferroptosis
With enough evidence demonstrating the occurrence of immunothrombosis in COVID-19 and other inflammatory conditions, as well as a clear association between deficient GSH and mediators of thrombosis and immunothrobosis, GSH may reside at the top of the cascade of biochemical events to reduce immunothrombosis