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Ang II is the main effector of the RAS and binds to angiotensin II type 1 receptor (AT 1 ), inducing an increase in blood pressure through vasoconstriction, enhanced circulating volume, catecholamine release, and improved cardiac contractility [6]

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EmirUERaatzSMcPhersonSHodgesJSTorkelsonCTawfikPet alNoninvasive quantification of ascorbate and glutathione concentration in the elderly human brain

This means that while its origin is rooted in a natural biological component, the compound itself is a manufactured entity, which has significant implications for its classification and oversight by regulatory bodies