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Ibutamoren increased GH and IGF-1 to youthful levels in older adults without suppressing cortisol or endogenous hormonal regulation. Chapman et al., The Journal of Clinical Endocrinology & Metabolism This makes MK-677 not only a valuable performance-enhancing compound but also a potential therapeutic agent for muscle wasting, hormonal decline, and age-related frailty

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Liang D, et al