These thresholds were determined in p53-null parental cell lines CAOV3, SKOV3, and OVCAR5, and IC 50 values were 27, 43, and 49 M, respectively (Fig
Am J Physiol Gastrointest Liver Physiol 297:G207-214
Rest assured, Glutathione is safe for individuals of all ages
10.1080/09546634.2021.1962000 [DOI] [PubMed] [Google Scholar] 69.Mazzilli S, Cosio T, Botti E, Petruzzellis A, Lanna C, Diluvio L, et al
Two natural products, (-)-Vestitol and Salviolone, were selected for further validation
10.1038/s41598-018-33385-z Summary Keywords nitazoxanide, methotrexate, hepatotoxicity, endoplasmic reticulum stress, rat Citation Mahmoud NM, Elshazly SM, El-shaarawy F, Zaitone SA, Aldahish AA, Ahmed GA, Fawzy MS, Aloyouni SY, Abed SY, Saeedi T and El-Sayed SS (2024) Nitazoxanide mitigates methotrexate hepatotoxicity in rats: role in inhibiting apoptosis and regulating endoplasmic reticulum stress