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Topical pain relief, physical therapy, or other non-pharmaceutical approaches may also be appropriate

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Haematologica (2010) 95:181422

Missing a single dose mid-cycle has minimal impact on overall anabolic response because receptor occupancy remains above baseline for 3648 hours post-injection, but missing multiple doses within a week creates gaps in receptor stimulation that can blunt peak anabolic signaling during the critical weeks 24 window