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Peptide WH was relatively stable in simulated gastrointestinal digestion and was able to maintain the IC 50 value for -glucosidase inhibition (17.03 0.05 mol/L), whereas WS significantly increased the IC 50 value after simulated digestion (24.71 0.02 mol/L to 44.63 0.03 mol/L) (68)

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The most pronounced inhibitory effects were observed at concentrations of 10 and 100 nM for each compound

Elevated levels of serum Interleukin-8 (IL-8) in T1DM individuals with poor glucose control may contribute to an inflammatory response that has shown to lower IGF-1 levels in chronic inflammatory diseases [74]