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This decline correlates with the reduced regenerative capacity that comes with aging, which partly explains why shoulder injuries heal more slowly in older individuals

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FDA has raised regulatory and safety concerns regarding certain BPC-157-related bulk substances used in compounding contexts, and the dietary supplement classification of BPC-157 products has been a topic of industry discussion through 2025 and into 2026

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Conclusion: AAPE activates HK proliferation and migration

5a and Supplementary Fig