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Moreover, results from various animal model experiments have indicated that resveratrol (RSV) can mitigate TMAO-induced AS by suppressing TMA formation, with the hepatic FXR-fibroblast growth factor 15 (FGF15) axis serving a critical role in resveratrol-induced bile acid (BA) synthesis (Li et al., 2021c)

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Additionally, semaglutide acts on receptors in the brain to reduce appetite and food intake, and it slows gastric emptying, promoting satiety