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Mechanical or inflammatory injury to the hypothalamus alters neuroendocrine secretion and contributes to systemic insulin resistance induced by inflammation/hyperglycemia, further impairing metabolic regulation and glucose uptake [60]

PMID: 135 DepommierCEverardADruartCPlovierHVan HulMVieira-SilvaSet al

Hosios AM, Hecht VC, Danai LV, Johnson MO, Rathmell JC, Steinhauser ML, Manalis SR, Vander Heiden MG

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Experiences vary, but preparation and documentation can make the process smoother

Observable outcomes can be seen in 4-8 weeks based on the treatment procedure and personal skin reaction