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A glycolytic phenotype is associated with prostate cancer progression and aggressiveness: a role for monocarboxylate transporters as metabolic targets for therapy

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These effects were achieved under reduced activation of noncanonical signaling pathways including receptor internalization and -arrestin recruitment, an initially surprising observation as these have previously been linked to increased GLP-1R responses when measured acutely 10,14,36

Insulin-like growth factor (IGF)-independent action of IGF-binding protein-3 in Hs578T human breast cancer cells

References 1.Yang Z., Hotterbeex P., Marent P.J., Cerin E., Thomis M., van Uffelen J

Clinical trials published in the Journal of the American Medical Association (JAMA) also showed improvements in blood pressure and cholesterol levels in some patients (source)