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When latent EBV reactivates and enters the lysogenetic phase, it causes the acute symptoms of infection once again 13
Common side effects include, but may not be limited to: pain or redness at the injection site mild diarrhea pruritus (itching) increased swelling joint pain dizziness headache nervousness or anxiety Serious side effects may include: allergic reactions peripheral vascular thrombosis hypokalemia (low potassium levels) pulmonary edema (fluid build-up around or in the lungs) thrombocytosis congestive heart failure There have been reports of anaphylactic shock and death after the parenteral administration of vitamin B12
Furthermore, the endogenously produced and secreted pyruvate in TNBC cell lines exhibited the capacity to markedly diminish the sensitivity of recipient cells to glutaminase inhibition through a paracrine mechanism [224]
Animal experimental evidence Osteoclast precursor (RAW264.7) experiment: AOD 9604 significantly inhibited RANKL induced osteoclast formation, reduced the number of TRAP positive multinucleated cells, and decreased bone resorption pit formation
