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Oxidized glutathione reflects stress
Thats why many peptide drugs are delivered subcutaneously (say, through an injector pen or insulin pump) and why it took so long to develop a pill version of semaglutide
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GAPDH was used as a loading control ( n = 3).( B ) cAMP levels in coronary effluents were measured at timed intervals during an initial 10-minute perfusion of WT hearts with either 6 nM GLP-1(2836), scrambled(2836) control (Scram), or buffer-only control (Cntl), or with 0.3 nM GLP-1, and were normalized to coronary flow (mL/min/g heart weight)