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Dual effects in pulsatile growth hormone secretion and clearance subserve the hyposomatotropism of obesity in man

Notably, SIRT1-deacetylated SnCE1 showed a similar deSUMOylase activity compared to acetylated wild type SnCE1 (Fig

When total B12 levels are difficult to interpret, measurement of holotranscobalamin (active B12), methylmalonic acid (MMA) , or homocysteine can provide a clearer picture of functional B12 status, though availability and interpretation vary (for example, MMA rises in renal impairment)

Braszko et al., 2008

This solvent was composed of 40 L of 50 mM NEM (Sigma-Aldrich) in a mixture of 80% methanol and 20% 10 mM ammonium formate (Sigma-Aldrich), combined with 40 L of 100% acetonitrile (Thermo Fisher)