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Among other important data, retatrutide did not show plateauing till the end of its trial duration - marking a shift from its established predecessors

3.9% (obesity) Pregnancy loss higher in all groups with metabolic risk (2329%) Live birth rate: 59% (GLP-1 RA group) Conclusion: Reassuring data with no signal for increased congenital malformations

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This is thought to result from increased sympathetic tone or direct effects on cardiac pacemaker cells

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