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Insulin-like Growth Factor-1 Long Arginine 3, or IGF-1 LR3, is a modified, long-acting analogue of endogenous IGF-1

PBMs have responded to gene therapies through a combination of prior authorization requirements (which serve as the primary utilization management tool), outcomes-based payment arrangements with manufacturers, and in some cases, carve-out arrangements where gene therapy coverage is managed separately from the standard pharmacy benefit

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