Clinical trials show semaglutide reduces HbA1c by 1.5 to 2 percentage points on average, with most patients achieving target ranges within three to six months
Personalized GLP-1 Therapy: PlexusDx Precision Peptide Genetic Testing in San Antonio PlexusDx offers San Antonio patients access to the Precision Peptide Genetic Test, a genetic analysis that evaluates 14 metabolic pathways and 49 peptides to identify how your body responds to GLP-1 therapy
It is likely that the peptide works through various biochemical pathways and may modify gene expression
In clinical trials, average weight loss ranged from around 15% of body weight over 68 weeks on Wegovy to around 22.5% over 72 weeks on Mounjaro, when combined with lifestyle changes
1o, p and 2i)
However, it may occur indirectly through mechanisms such as dehydration from gastrointestinal side effects, blood pressure changes, or hypoglycemia, particularly in patients taking insulin or sulfonylureas