You should contact your doctor immediately if you experience sudden and severe stomach pain, chills, constipation, nausea, vomiting, fever, or lightheadedness
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The corrin ring structure, which is the molecular backbone of vitamin B12, appears to alter the pharmacokinetic profile in a way that reduces central nervous system exposure to the emetogenic (nausea-causing) effects while preserving the metabolic benefits
Tirzepatide Once Weekly for the Treatment of Obesity. JAMA Internal Medicine , 2023
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