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Adjustments are made gradually to help minimize side effects and support sustainable outcomes

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Stroke in the 21st century: a snapshot of the burden, epidemiology, and quality of life

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A second mechanism leading to hepatocellular hyperplasia is a consequence of shifts of existing hepatocyte populations from binucleated hepatocytes to mononucleated cells and shifts from a mononucleated tetraploid hepatocyte to two diploid hepatocytes (cytokinesis without nuclear duplication)