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This would increase the understanding of mechanisms of action of the drugs currently used and aid the development of novel effective therapies to treat specific mitochondrial functions that might be used as the main therapy or as adjunctive treatment, especially for subjects that do not fully respond to conventional therapies
In Figures 4A, B, GHK and the two targeting peptides exhibited negligible cytotoxicity in human keratinocyte (HaCaT) and human fibroblast (HFF-1) at concentrations up to 200 g/mL that was used for the following experiments
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Composite biomarkers for assessing Duchenne muscular dystrophy: an initial assessment
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