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Notably, the administration of L-carnitine ameliorates these alterations, as evidenced by reduced MDA and protein carbonyl levels, increased TAC, and decreased TOS content

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The primary reviewers were not blinded to the authors, institutions or source of publication at any time during the selection process

With the lung infiltration of neutrophils and macrophages triggered by CS, proinflammatory cytokines such as interleukin -1(IL-1) and tumor necrosis factor- (TNF-) induce a cascade of amplification effects of inflammation, and activate nuclear factor- B (NF- B) (Di Stefano et al., 2002)