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Cagrilintide was studied up to 2.4 mg

76 Other recent analyses have revealed survodutide, tirzepatide, and retatrutide to each significantly reduce liver fat with no evidence of worsening in markers of liver fibrosis.77, 78, 79 Depression and suicidality Most studies evaluating depression and GLP-1 RA use were conducted in those with T2DM and indicate no increased risk

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The strongest evidence for DSIP comes from small (n under 50), mostly 1970s to 1990s European studies

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