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doi: 10.1016/j.coph.2004.08.008

Animal models provide proof of concept but do not translate directly to human androgenetic alopecia, which involves hormonal mechanisms absent in mouse models

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However, as with any topically applied active ingredient, reactions can occur, particularly in individuals with sensitive skin or pre-existing scalp conditions such as seborrhoeic dermatitis or psoriasis

This can also help with removing dead skin cells, remove old blemishes, help improve the overall tone of the skin and improve immune system

An important protective role of NRF2 against EtOH-induced oxidative stress and lipotoxicity has been established in in vivo and in vitro studies 47