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In a proteomic study on postmortem samples of PD patients it was shown that GSTP1-1 levels are increased in PD patients at advanced stages

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Under physiological conditions, more than 98% of the total GSH pool exists in the reduced form, thereby shaping cellular redox potential and influencing proliferation, differentiation, and cell death 5 .Although the GSH/GSSG ratio has long been regarded as an indicator of cellular redox status, recent live-cell studies using genetically encoded redox sensors indicate that increases in GSSG are typically transient and compartmentalized rather than sustained intracellular accumulations 6,7

Instrumentation for detecting sulphur isotopes as biosignatures on Europa and Ganymede by forthcoming missions

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