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1 Endotoxin limits should be calculated using the maximum drug dose intended for intravenous (IV) administration

N Engl J Med 312:818822 Wellman AS, Metukuri MR, Kazgan N, Xu X, Xu Q, Ren NS, Czopik A, Shanahan MT, Kang A, Chen W (2017) Intestinal epithelial sirtuin 1 regulates intestinal inflammation during aging in mice by altering the intestinal microbiota

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