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If successful, this could lay the foundation for more targeted and effective treatments and delivery options, particularly for patients at high risk of severe periodontal diseases, such as the elderly, diabetics, and immunocompromised. The study included multiple students from different programs, including undergraduate students at the Penn Center for Undergraduate Research and Fellowships , dental students from Penn Dental Medicines summer research program, and a graduate student from Penn Dental Medicines DScD program
in colon tissue, assessing NO levels and oxidative stress (MDA levels) (as result of the lysis of endothelial cells) and ischemia/reperfusion injury, both as a spontaneous course [when blood supply was deprived via ligation (IC rats)] and a more exaggerated course [after ligation removal (IC + RL rats)] in immediate post-ligation time
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