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Once inside the cell, Fe 3+ is reduced to Fe 2+ via six-transmembrane epithelial antigen of prostate 3 (STEAP3) and transported into the cytosol by divalent metal transporter 1 (DMT1) and ZRT/IRT-like proteins 8 and 14 (ZIP8/14) (Wang et al., 2025d)

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Cyclic heptapeptide alpha-MSH analog (MC3R/MC4R agonist) Formula C50H68N14O10 Molecular weight 1025.18 g/mol Form Lyophilized powder CAS / ID Bremelanotide Independently tested

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doi: 10.3390/biom10070988 74 WuYPiDZhouSYiZDongYWangWet al