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If the FDA will require outcomes trials for future approvals in obesity, this will add considerable time and cost to drug development

Thickens cervical mucus : The cervix is the opening to the uterus

Semaglutide produced greater weight loss than placebo across the STEP trial program, but we will not quote a specific average here because individual results vary widely

Moreover, GLP-1 preserves mitochondrial integrity by inhibiting MPTP-induced opening and cytochrome c release and strengthens antioxidant defences by synthesising enzymes like catalase and superoxide dismutase [32]

GIP Receptor Effects: This complements the GLP-1 effects, further boosting insulin responsiveness post-meals and contributing to lessened hunger pangs

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