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Roles and crosstalks of macrophages in diabetic nephropathy

JCO Precis Oncol 6:e2200275, 2022

It helps the body manage blood sugar and reduce appetite by mimicking a natural hormone called GLP-1 (glucagon-like peptide-1)

Clinical trials show that approximately 2540% of participants experience nausea during dose escalation weeks, with most reporting resolution by day 1014 of each new dose level

LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: From discovery to clinical proof of concept Coskun T, Sloop KW, Loghin C, et al

As described in the methods section, stable transfections of GSTM3 knockdown in PANC-1 cells and GSTM3 overexpression in MIA PaCa-2 cells were established using lentivirus vectors