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Amylin, a neuroendocrine anorexigenic polypeptide hormone, with its multi-faceted effects in glucose regulation, weight management and potential CV and neuroprotective functions, represents an attractive new therapeutic target, albeit not without challenges and limitations [29]

Research to date highlights MOTS-cs ability to promote metabolic homeostasis (improving insulin sensitivity, encouraging fat utilization, and preventing diet-induced metabolic disorders) as well as its potential to mitigate aspects of aging (preserving muscle function, bone density, vascular health, and more)

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The control group received the same amount of intraperitoneal saline

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