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A separate analysis of the STEP 1 data found that lean mass was reduced by 6.92 kg with a total weight reduction of 15.3 kg, meaning roughly 45 percent of the weight lost was lean mass

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This is a mechanism no approved drug currently uses Phase 2 trials showed up to 24% body weight reduction over 48 weeks, meaningfully exceeding tirzepatide and semaglutide outcomes Phase 3 trials are currently underway

Long-term side risks could consist of the body generating antibodies against the drug, which could reduce its efficacy or cause new side effects

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